Observing enzyme ternary transition state analogue complexes by 19F NMR spectroscopy† †Electronic supplementary information (ESI) available: Supporting Figures, HQSC NMR spectra, LC-MS/MS data and X-ray diffraction refinement data are described. See DOI: 10.1039/c7sc04204c

Macrocycle-assisted synthesis of non-stoichiometric silver(i) halide electrocatalysts for efficient chlorine evolution reaction† †Electronic supplementary information (ESI) available: Supporting figures, high-resolution ESI-MS, TEM images, CV plots and NMR, FT-IR, UV-vis, XPS and AES spectra. Refinement details and crystal data for 1–3 are also available. CCDC 1527294–1527296. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c7sc00575j Click here for additional data file. Click here for additional data file.

A specific fluorescent probe reveals compromised activity of methionine sulfoxide reductases in Parkinson's disease† †Electronic supplementary information (ESI) available: The characterization of probes, experimental procedures, supporting data and original spectra (1H NMR, 13C NMR, and MS) of the final 23 compounds. See DOI: 10.1039/c6sc04708d Click here for additional data file.

NMR and TRLFS studies of Ln(iii) and An(iii) C5-BPP complexes† †Electronic supplementary information (ESI) available: LIFDI-MS spectra and additional NMR spectra. See DOI: 10.1039/c4sc03103b

Divergent unprotected peptide macrocyclisation by palladium-mediated cysteine arylation† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c6sc05454d Click here for additional data file.

1. General Experimental Details 2. Oxidative Addition Complexes and Synthetic Procedures 3. Peptide Synthesis and LC-MS Characterisation 4. Macrocyclisation Reactions and LC-MS Characterisation 5. C-CA Protein Expression 6. BioLayer Interferometry Binding 7. Lipophilicity, Phospholipid Affinity, Volume of Distribution, and Human Serum Albumin Binding Data 8. ICP-MS Analysis 9. References 10. NM...

Well-defined coinage metal transfer agents for the synthesis of NHC-based nickel, rhodium and palladium macrocycles† †Electronic supplementary information (ESI) available: 1H and 13C{1H} NMR, and ESI-MS spectra of new complexes. Selected 1H NMR data for transmetallation reactions of 2 and 4. CCDC 1470494–1470497. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c6dt01263a Click here for additional data file. Click here for additional data file.

With a view to use as carbene transfer agents, well-defined silver(i) and copper(i) complexes of a macrocyclic NHC-based pincer ligand, bearing a central lutidine donor and a dodecamethylene spacer [CNC-(CH2)12, 1], have been prepared. Although the silver adduct is characterised by X-ray diffraction as a dinuclear species anti-[Ag(μ-1)]2(2+), variable temperature measurements indicate dynamic s...